Upstream Bio Inc (UPB)

Currency in USD
7.28
+0.36(+5.20%)
Closed·
7.33+0.05(+0.69%)
·
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Fair Value
Day's Range
6.817.42
52 wk Range
5.8533.68
Key Statistics
Prev. Close
7.28
Open
6.9
Day's Range
6.81-7.42
52 wk Range
5.85-33.68
Volume
560.98K
Average Volume (3m)
605.58K
1-Year Change
-34.5912%
Book Value / Share
5.59
Fair Value
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Fair Value Upside
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UPB Scorecardpro icon
Company’s Health
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Fair Value
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Fair Price
Upside
Price Target
38.25
Upside
+425.41%
Members' Sentiments
Bearish
Bullish
ProTips
Quickly burning through cash

Upstream Bio Inc News & Analysis

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Technical Analysis

Summary
Strong Sell
Sell
Neutral
Buy
Strong Buy
Strong Buy
Technical Indicators
Strong Buy
Moving Averages
Strong Buy

Analyst Ratings

7 Buy
2 Hold
0 Sell
Ratings:
9 analysts
Overall Consensus
Buy

Analysts 12-Month Price Target:

Average 38.25
(+425.41% Upside)
Firm
ArticlePositionPrice TargetUpside / DownsideFrom Price TargetActionDate
JPMorgan
Hold8.00+9.89%35.00Downgrade12-06-2026
H.C. Wainwright
Buy36.00+394.51%-New Coverage03-06-2026
Mizuho
Buy50.00+586.81%51.00Maintain14-05-2026
Truist Securities
Buy43.00+490.66%47.00Maintain02-04-2026
Evercore ISI
Hold15.00+106.04%40.00Downgrade27-03-2026

Earnings

Latest Release
13-05-2026
EPS / Forecast
-0.75 / -0.85
Revenue / Forecast
1.03M / --
EPS Revisions
Last 90 days

UPB Income Statement

Compare UPB to Peers and Sector

Metrics to compare
UPB
Peers
Sector
Relationship
P/E Ratio
−2.5x−2.4x−0.4x
PEG Ratio
−0.17−0.070.00
Price/Book
1.3x2.5x2.6x
Price / LTM Sales
119.3x9.8x3.0x
Upside (Analyst Target)
-80.5%51.3%
Fair Value Upside
Unlock4.5%7.3%Unlock

Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases focusing on severe respiratory disorders. It offers verekitug, which is in Phase 2 trials for the treatment of severe asthma and chronic rhinosinusitis with nasal polyps and chronic obstructive pulmonary disease and in Phase I clinical trial for treating chronic obstructive pulmonary disease. The company was incorporated in 2021 and is headquartered in Waltham, Massachusetts.

Ownership

Ownership Overview

Type
Common Stock Held% of Shares OutstandingMarket Value
Mutual Funds & ETFs
15.80M29.03%115.02M
Other Institutional Investors
57.81M70.97%420.87M
Public Companies & Retail Investors
0.000.00%0.00
Total
73.61M100.00%535.89M

Top Holders

Holder
% of holding
Shares Held
Date Reported
Value (In 1,000s)
FMR LLC14.89%81,01,53858,979
OrbiMed Advisors LLC10.46%56,93,58941,449

FAQ

What Is the Upstream Bio (UPB) Share Price Today?

The Upstream Bio share price today is 7.28.

What is the current Upstream Bio (UPB) share price and day range?

As of 02-07-2026, the Upstream Bio share price is 7.28, with a previous close of 7.28. The share price has ranged from 6.81 to 7.42 today, while the 52-week range spans from 5.85 to 33.68.

What Is the Upstream Bio Market Cap?

As of today, Upstream Bio market cap is 396.18M.

What Is the Upstream Bio (UPB) Share Price Target?

The average 12-month share price target for Upstream Bio is 38.25, with a high estimate of 75 and a low estimate of 8. 7 analysts recommend buying, while 0 suggest selling, with an overall rating of Buy and +425.41% Upside potential.

What Is Upstream Bio's Earnings Per Share (TTM)?

The Upstream Bio EPS (TTM) is -2.90.

When Is the Next Upstream Bio Earnings Date?

Upstream Bio will release its next earnings report on 12-08-2026.

From a Technical Analysis Perspective, Is UPB a Buy or Sell?

Based on moving averages and other technical indicators, the daily buy/sell signal is Buy.

What Stock Exchange Does Upstream Bio Trade On?

Upstream Bio is listed and trades on the Nasdaq Stock Exchange.

What Is the Stock Symbol for Upstream Bio?

The stock symbol for Upstream Bio is "UPB."

How Many Times Has Upstream Bio Stock Split?

Upstream Bio has split 0 times.

How Many Employees Does Upstream Bio Have?

Upstream Bio has 75 employees.

What Is the UPB Premarket Price?

UPB's last pre-market stock price is 7.33. The pre-market share volume is 30.00, and the stock has changed by 0.05, or 0.69%.
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