Rhythm Pharmaceuticals Inc (RYTM)

Currency in USD
81.77
-0.35(-0.43%)
Real-time Data·
Earnings results expected in 5 days
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Fair Value
Day's Range
81.6784.00
52 wk Range
55.31122.20
Key Statistics
Prev. Close
82.12
Open
82.04
Day's Range
81.67-84
52 wk Range
55.31-122.2
Volume
56.7K
Average Volume (3m)
830.53K
1-Year Change
25.4333%
Book Value / Share
2.08
Fair Value
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Fair Value Upside
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RYTM Scorecardpro icon
Company’s Health
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Fair Value
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Fair Price
Upside
Price Target
137.67
Upside
+68.36%
Members' Sentiments
Bearish
Bullish
ProTips
Stock price movements are quite volatile

Rhythm Pharmaceuticals Inc News & Analysis

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Technical Analysis

Summary
Strong Sell
Sell
Neutral
Buy
Strong Buy
Strong Sell
Technical Indicators
Strong Sell
Moving Averages
Strong Sell

Analyst Ratings

15 Buy
1 Hold
0 Sell
Ratings:
16 analysts
Overall Consensus
Strong Buy

Analysts 12-Month Price Target:

Average 137.67
(+68.36% Upside)
Firm
ArticlePositionPrice TargetUpside / DownsideFrom Price TargetActionDate
Leerink Partners
Buy142.00+73.38%-Maintain26-03-2026
TD Cowen
Buy130.00+58.73%-Maintain24-03-2026
H.C. Wainwright
Buy105.00+28.21%100.00Maintain23-03-2026
H.C. Wainwright
Buy100.00+22.10%110.00Maintain18-03-2026
RBC Capital
Buy130.00+58.73%140.00Maintain17-03-2026

Rhythm Pharmaceuticals Inc Earnings Call Summary for Q4/2025

  • Rhythm Pharmaceuticals beat Q4 2025 expectations with EPS of -$0.73 vs. forecast -$0.82 and revenue of $57.3M vs. expected $55.24M.
  • Full-year 2025 revenue reached $194.8M, up 50% from 2024, driven by 10% increase in patients on IMCIVREE therapy globally.
  • Stock rose 3.38% to $102.5 in premarket trading; analysts set price targets between $125-$167, suggesting 43% upside potential.
  • Q4 revenue split: $39M U.S. (68%) and $18.3M ex-U.S. (32%); company maintains 89.4% gross profit margin despite rising SG&A expenses.
  • Management highlighted positive Bivamelagon HO trial results and commitment to pipeline expansion while managing operational cost pressures.
Last Updated: 26-02-2026, 07:46 pm
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Earnings

Latest Release
26-02-2026
EPS / Forecast
-0.73 / -0.82
Revenue / Forecast
57.3M / 55.24M
EPS Revisions
Last 90 days

RYTM Income Statement

Compare RYTM to Peers and Sector

Metrics to compare
RYTM
Peers
Sector
Relationship
P/E Ratio
−27.9x−1.8x−0.5x
PEG Ratio
−0.98−0.040.00
Price/Book
40.6x4.6x2.6x
Price / LTM Sales
29.7x19.2x3.2x
Upside (Analyst Target)
70.5%88.9%50.8%
Fair Value Upside
Unlock10.3%7.7%Unlock

Rhythm Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the rare neuroendocrine diseases in the United States and internationally. The company’s lead product candidate is IMCIVREE (setmelanotide), a rare melanocortin-4 receptor for the treatment of pro-opiomelanocortin (POMC), proprotein convertase subtilisin/kexin type 1, leptin receptor (LEPR) deficiency obesity, Bardet-Biedl and Alström syndrome, Prader-Willi syndrome, and hypothalamic obesity. It is in Phase 3 clinical trials for treating acquired hypothalamic obesity, congenital hypothalamic obesity, pro-opiomelanocortin (POMC) and LEPR insufficiency obesities, SRC1 deficiency obesity, and SH2B1 deficiency obesity; and in phase 2 clinical trails for the treatment of Prader-Willi syndrome and MC4R deficiency. The company is also developing bivamelagon, an investigational oral small molecule MC4R agonist that is in phase 2 clinical trial for the treatment of MC4R pathway diseases; and RM-718, a next generation MC4R peptide agonist that is in phase 1 clinical trial for the treatment of hypothalamic obesity. The company was formerly known as Rhythm Metabolic, Inc. and changed its name to Rhythm Pharmaceuticals, Inc. in October 2015. Rhythm Pharmaceuticals, Inc. was founded in 2008 and is headquartered in Boston, Massachusetts.

Employees
414

Ownership

Ownership Overview

Type
Common Stock Held% of Shares OutstandingMarket Value
Mutual Funds & ETFs
32.61M47.75%2.74B
Other Institutional Investors
49.07M52.25%4.13B
Public Companies & Retail Investors
0.000.00%0.00
Total
81.68M100.00%6.88B

Top Holders

Holder
% of holding
Shares Held
Date Reported
Value (In 1,000s)
RA Capital Management, L.P.9.76%66,66,8375,47,481
BlackRock, Inc.9.22%62,97,3335,17,137

FAQ

What Is the Rhythm Pharma (RYTM) Share Price Today?

The Rhythm Pharma share price today is 81.77.

What is the current Rhythm Pharma (RYTM) share price and day range?

As of 30-04-2026, the Rhythm Pharma share price is 81.77, with a previous close of 82.12. The share price has ranged from 81.67 to 84.00 today, while the 52-week range spans from 55.31 to 122.20.

What Is the Rhythm Pharma Market Cap?

As of today, Rhythm Pharma market cap is 5.59B.

What Is the Rhythm Pharma (RYTM) Share Price Target?

The average 12-month share price target for Rhythm Pharma is 137.67, with a high estimate of 158 and a low estimate of 105. 15 analysts recommend buying, while 0 suggest selling, with an overall rating of Strong Buy and +68.36% Upside potential.

What Is Rhythm Pharma's Earnings Per Share (TTM)?

The Rhythm Pharma EPS (TTM) is -3.11.

When Is the Next Rhythm Pharma Earnings Date?

Rhythm Pharma will release its next earnings report on 05-05-2026.

From a Technical Analysis Perspective, Is RYTM a Buy or Sell?

Based on moving averages and other technical indicators, the daily buy/sell signal is Strong Sell.

What Stock Exchange Does Rhythm Pharma Trade On?

Rhythm Pharma is listed and trades on the Nasdaq Stock Exchange.

What Is the Stock Symbol for Rhythm Pharma?

The stock symbol for Rhythm Pharma is "RYTM."

How Many Times Has Rhythm Pharma Stock Split?

Rhythm Pharma has split 0 times.

How Many Employees Does Rhythm Pharma Have?

Rhythm Pharma has 414 employees.

What Is the RYTM Premarket Price?

RYTM's last pre-market stock price is 82.38. The pre-market share volume is 980.00, and the stock has changed by 0.26, or 0.32%.

What Is the RYTM After Hours Price?

RYTM's last after hours stock price is 81.07, the stock has changed by -1.05, or -1.28%.
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