Personalis Inc (PSNL)

Currency in USD
5.900
+0.120(+2.08%)
Closed·
5.954+0.054(+0.91%)
·
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Fair Value
Day's Range
5.7205.975
52 wk Range
3.84011.500
Key Statistics
Prev. Close
5.78
Open
5.74
Day's Range
5.72-5.975
52 wk Range
3.84-11.5
Volume
1.72M
Average Volume (3m)
1.66M
1-Year Change
38.4977%
Book Value / Share
2.94
Fair Value
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Fair Value Upside
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PSNL Scorecardpro icon
Company’s Health
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Fair Value
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Fair Price
Upside
Price Target
11.286
Upside
+91.28%
Members' Sentiments
Bearish
Bullish
ProTips
2 analysts have revised their earnings downwards for the upcoming period

Personalis Inc News & Analysis

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Technical Analysis

Summary
Strong Sell
Sell
Neutral
Buy
Strong Buy
Strong Buy
Technical Indicators
Strong Buy
Moving Averages
Buy

Analyst Ratings

6 Buy
1 Hold
0 Sell
Ratings:
7 analysts
Overall Consensus
Strong Buy

Analysts 12-Month Price Target:

Average 11.286
(+91.28% Upside)
Firm
ArticlePositionPrice TargetUpside / DownsideFrom Price TargetActionDate
Morgan Stanley
Hold10.00+69.49%11.00Maintain04-03-2026
Needham
Buy12.00+103.39%10.00Maintain27-02-2026
BTIG
Buy13.00+120.34%-Maintain27-02-2026
Guggenheim
Buy13.00+120.34%12.00Maintain26-01-2026
Morgan Stanley
Hold11.00+86.44%-New Coverage02-12-2025

Personalis Inc Earnings Call Summary for Q4/2025

  • Q4 2025 EPS of -$0.26 beat forecast of -$0.30 by 13.33%; revenue of $17.3M missed estimates by 1.42%, up 3% YoY
  • Stock surged 8.66% aftermarket despite revenue miss; gross margin compressed to 11% while net loss widened to $23.8M from $16.4M YoY
  • Company shifting strategy from low-margin projects to high-value MRD partnerships; Medicare coverage expansion driving growth
  • 2026 guidance: 43K-45K clinical tests expected; MRD revenue from biopharma partnerships projected at $20M-$21M
  • Operating expenses rose 19.8% YoY to $27.2M; margin compression expected to continue into 2026 due to unreimbursed test costs
Last Updated: 27-02-2026, 04:56 am
Read Full Transcript

Earnings

Latest Release
26-02-2026
EPS / Forecast
-0.26 / -0.30
Revenue / Forecast
17.3M / 17.55M
EPS Revisions
Last 90 days

PSNL Income Statement

Compare PSNL to Peers and Sector

Metrics to compare
PSNL
Peers
Sector
Relationship
P/E Ratio
−7.6x−1.5x−0.5x
PEG Ratio
−0.23−0.010.00
Price/Book
2.4x0.5x2.6x
Price / LTM Sales
8.9x1.7x3.3x
Upside (Analyst Target)
86.3%58.3%47.1%
Fair Value Upside
Unlock33.5%6.2%Unlock

Personalis, Inc. develops, markets, and sells advanced cancer genomic tests and services in the United States and internationally. The company offers NeXT Personal, a tumor-informed liquid biopsy test for detection of minimal residual disease (MRD), therapy response and recurrence monitoring in solid tumor cancers; and ImmunoID NeXT, a tissue-based service that combines whole exome and whole transcriptome sequencing data with advanced analytics to provide a multi-dimensional view of the tumor and the tumor microenvironment from a single sample. It also provides NeXT Personal Dx, a tumor-informed liquid biopsy test for the detection of MRD; and NeXT Dx, a tumor profiling test that is used to help select therapy for a cancer patient and identify potential clinical trials for a patient. In addition, the company performs whole exome sequencing of cancer tissue and matched blood samples for diagnostic companies as an input to their products; and whole genome sequencing on human samples for research projects, such as population sequencing initiatives. Its services are used by pharmaceutical companies for translational research, biomarker discovery, the development of personalized cancer therapies, and for clinical trials, as well as tests are used by physicians to detect residual or recurrent cancer in patients, monitor cancer response to therapy, and uncover insights for therapy selection. The company’s customers include pharmaceutical companies, biopharmaceutical companies, diagnostics companies, universities, non-profits, government entities, and cancer patients. The company has strategic collaboration with Tempus AI, Inc. to bring testing to colorectal cancer patients. Personalis, Inc. was incorporated in 2011 and is headquartered in Fremont, California.

Ownership

Ownership Overview

Type
Common Stock Held% of Shares OutstandingMarket Value
Mutual Funds & ETFs
28.12M26.87%162.55M
Other Institutional Investors
66.48M63.51%384.28M
Public Companies & Retail Investors
10.07M9.62%58.21M
Total
104.68M100.00%605.04M

Top Holders

Holder
% of holding
Shares Held
Date Reported
Value (In 1,000s)
Merck & Co., Inc.13.42%1,40,44,94381,180
Tempus AI, Inc.12.46%1,30,39,06775,366

FAQ

What Is the Personalis (PSNL) Share Price Today?

The Personalis share price today is 5.900.

What is the current Personalis (PSNL) share price and day range?

As of 05-05-2026, the Personalis share price is 5.900, with a previous close of 5.780. The share price has ranged from 5.720 to 5.975 today, while the 52-week range spans from 3.840 to 11.500.

What Is the Personalis Market Cap?

As of today, Personalis market cap is 617.600M.

What Is the Personalis (PSNL) Share Price Target?

The average 12-month share price target for Personalis is 11.286, with a high estimate of 13 and a low estimate of 10. 6 analysts recommend buying, while 0 suggest selling, with an overall rating of Strong Buy and +91.28% Upside potential.

What Is Personalis's Earnings Per Share (TTM)?

The Personalis EPS (TTM) is -0.911.

When Is the Next Personalis Earnings Date?

Personalis will release its next earnings report on 07-05-2026.

From a Technical Analysis Perspective, Is PSNL a Buy or Sell?

Based on moving averages and other technical indicators, the daily buy/sell signal is Strong Sell.

What Stock Exchange Does Personalis Trade On?

Personalis is listed and trades on the Nasdaq Stock Exchange.

What Is the Stock Symbol for Personalis?

The stock symbol for Personalis is "PSNL."

How Many Times Has Personalis Stock Split?

Personalis has split 0 times.

How Many Employees Does Personalis Have?

Personalis has 260 employees.

What Is the PSNL Premarket Price?

PSNL's last pre-market stock price is 5.850. The pre-market share volume is 12,350.000, and the stock has changed by 0.070, or 1.210%.

What Is the PSNL After Hours Price?

PSNL's last after hours stock price is 5.954, the stock has changed by 0.054, or 0.910%.
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