Investing.com – U.S. equities were mixed at the close on Wednesday, as gains in the Technology , Healthcare and Telecoms sectors propelled shares higher while losses in the Oil & Gas , Utilities and Consumer Services sectors led shares lower.
The biggest gainers of the session on the Dow Jones Industrial Average were Pfizer Inc (NYSE: PFE ), which rose 2.33% or 0.79 points to trade at 34.72 at the close. Apple Inc (NASDAQ: AAPL ) added 1.59% or 4.57 points to end at 292.65 and 3M Company (NYSE: MMM ) was up 1.44% or 2.11 points to 148.96 in late trade.
Biggest losers included Walt Disney Company (NYSE: DIS ), which lost 3.77% or 4.83 points to trade at 123.36 in late trade. Chevron Corp (NYSE: CVX ) declined 2.65% or 2.67 points to end at 98.04 and Exxon Mobil Corp (NYSE: XOM ) shed 2.20% or 1.19 points to 53.01.
The top performers on the S&P 500 were TJX Companies Inc (NYSE: TJX ) which rose 7.15% to 63.99, Gilead Sciences Inc (NASDAQ: GILD ) which was up 6.56% to settle at 74.70 and CME Group Inc (NASDAQ: CME ) which gained 5.69% to close at 220.18.
The worst performers were Royal Caribbean Cruises Ltd (NYSE: RCL ) which was down 8.05% to 82.34 in late trade, Norwegian Cruise Line Holdings Ltd (NYSE: NCLH ) which lost 7.89% to settle at 36.21 and TripAdvisor Inc (NASDAQ: TRIP ) which was down 7.85% to 23.61 at the close.
The top performers on the NASDAQ Composite were Tonix Pharmaceuticals Holding Corp (NASDAQ: TNXP ) which rose 122.55% to 0.900, Co-Diagnostics Inc (NASDAQ: CODX ) which was up 106.26% to settle at 8.900 and Vir Biotechnology Inc (NASDAQ: VIR ) which gained 60.95% to close at 34.98.
The worst performers were Aptorum Group Ltd Class A (NASDAQ: APM ) which was down 53.47% to 6.70 in late trade, Microvision Inc (NASDAQ: MVIS ) which lost 53.05% to settle at 0.2744 and Menlo Therapeutics Inc (NASDAQ: MNLO ) which was down 32.27% to 2.98 at the close.
Declining stocks outnumbered rising ones by 1928 to 907 and 68 ended unchanged; on the Nasdaq Stock Exchange, 1715 fell and 956 advanced, while 60 ended unchanged on the New York Stock Exchange.
The CBOE Volatility Index , which measures the implied volatility of S&P 500 options, was down 1.04% to 27.56.
In commodities trading, Gold Futures for April delivery was down 0.43% or 7.15 to $1642.85 a troy ounce. Meanwhile, Crude oil for delivery in April fell 2.57% or 1.28 to hit $48.62 a barrel, while the May Brent oil contract rose 0.09% or 0.05 to trade at $52.84 a barrel.
EUR/USD was up 0.07% to 1.0887, while USD/JPY fell 0.05% to 110.36.
The US Dollar Index Futures was up 0.19% at 99.090.
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