* Miners weigh down FTSE 100
* Spain's Unicaja jumps on Liberbank merger
* Thin volumes keep markets volatile
(Updates to market close)
By Sruthi Shankar and Ambar Warrick
Dec 30 (Reuters) - European stocks ended a five-day winning streak on Wednesday as investors locked in recent gains, although positive vaccine and Brexit trends pointed to a stronger 2021 for regional markets.
The pan-European STOXX 600 .STOXX edged 0.3% lower, still staying close to a 10-month high. The index is set to shed more than 3% this year, owing to disruptions caused by a second wave of coronavirus infections towards the end of the year.
But the signing of a Brexit deal, coupled with the rollout of a vaccine programme has made investors optimistic about a recovery in 2021.
"There are some things happening out there that suggests that risk appetite is strong," said Russ Mould, investment director at AJ Bell.
"If you're looking through to 2021, we're hoping that the vaccines will begin to counteract the effect of the pandemic, and hopefully economic activity will begin to normalise."
Travel and leisure stocks .SXTP , one of the worst performing sectors this year, added 0.2%, as they stand to be among the top beneficiaries of a coronavirus vaccine.
German shares .GDAXI ended a shortened session about 0.3% lower, in their last trading day this year. But they added more than 3% in 2020, thanks to flows into heavyweight technology stocks.
Spanish lender Unicaja UNI.MC rose 2.1%, while Liberbank LBK.MC was down 4.1%, after they announced an all-in share deal that would create the country's fifth-biggest bank. deal marks an acceleration of the sector's consolidation after the approval of a merger between state-owned Bankia BKIA.MC and Caixabank CABK.MC earlier this month.
The wider banking index .SX7P fell 0.3% and is among the worst performing sectors this year alongside energy, as mounting bad loans due to the impact of the pandemic and record low interest rates hammered the appeal for the sector.
UK stocks ended lower despite the local approval of AstraZeneca's AZN.L COVID-19 vaccine. Resource stocks were the biggest weight on the benchmark blue-chip index .FTSE , due to weakness in metal prices. IRONORE/ MET/L
Meanwhile, Wall Street indexes hit all-time highs this week on hopes that U.S. lawmakers will approve a large fiscal stimulus package despite delays.
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