At the close in Tokyo, the Nikkei 225 lost 0.19%.
The biggest gainers of the session on the Nikkei 225 were Eisai Co., Ltd. (T: 4523 ), which rose 19.35% or 1500.0 points to trade at 9251.0 at the close. Kawasaki Kisen Kaisha, Ltd. (T: 9107 ) added 4.92% or 160.0 points to end at 3415.0 and Daiichi Sankyo Co., Ltd. (T: 4568 ) was up 4.92% or 116.5 points to 2483.0 in late trade.
Biggest losers included Sumitomo Metal Mining Co., Ltd. (T: 5713 ), which lost 4.07% or 198.0 points to trade at 4665.0 in late trade. Oji Holdings Corp. (T: 3861 ) declined 3.12% or 21.0 points to end at 653.0 and Daikin Industries, Ltd. (T: 6367 ) shed 3.12% or 660.0 points to 20520.0.
Advancing stocks outnumbered falling ones by 2239 to 1240 and 252 ended unchanged on the Tokyo Stock Exchange.
The Nikkei Volatility , which measures the implied volatility of Nikkei 225 options, was unchanged 0% to 20.15.
In commodities trading, Crude oil for July delivery was down 0.61% or 0.42 to $68.81 a barrel. Meanwhile, Brent oil for delivery in August fell 0.64% or 0.46 to hit $71.03 a barrel, while the August Gold Futures contract fell 0.07% or 1.35 to trade at $1897.45 a troy ounce.
USD/JPY was up 0.22% to 109.48, while EUR/JPY rose 0.06% to 133.23.
The US Dollar Index Futures was up 0.18% at 90.110.
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