Vor Biopharma Inc. operates as a clinical-stage cell and genome engineering company. The company offers the Vor Bio platform, a technology platform for the treatment of acute myeloid leukemia (AML) and other blood cancers. It develops tremtelectogene empogeditemcel (trem-cel), a genome-edited hematopoietic stem and progenitor allogeneic donor product candidate to treat acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), and other blood cancers; trem-cel in combination with Mylotarg to treat patients in VBP101, which is in phase 1 / 2; and VCAR33, a CAR-T therapy designed to target CD33, which is under preclinical studies to treat AML post-transplant. The company also develops trem-cel + VCAR33 treatment system, CD33-directed CAR-T program, which is under pre-clinical studies for the treatment of AML; VADC45 for the treatment of hematologic malignancies, conditioning, and immune reset, which is under preclinical studies; and CD33-CLL1 treatment system made with CD33-CLL1 multiplex-edited HSC therapy and a CD33-CLL1 multi-specific CAR-T therapy, which is under preclinical studies for the treatment of AML. It has a license agreement with Columbia University and the National Institutes of Health for patents; and with Editas Medicine, Inc. for ex-vivo Cas9 gene-edited HSC therapies for the treatment and/or prevention of hematological malignancies. The company was incorporated in 2015 and is headquartered in Cambridge, Massachusetts.
AML Breakthrough | Vor Biopharma's trem-cel + Mylotarg combo shows promise in improving relapse-free survival for AML patients, with key data expected in 2025 |
Financial Runway | $91.9M cash position and $56M PIPE extend operations into Q1 2026, supporting critical clinical milestones despite negative EPS forecasts |
Market Potential | Analyst price targets range from $5 to $18, reflecting significant upside potential in the competitive oncology therapeutics landscape |
Strategic Expansion | Explore Vor's plans for a pivotal two-year controlled trial and potential applications of its technology beyond AML, diversifying its pipeline |
Metrics to compare | VOR | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipVORPeersSector | |
---|---|---|---|---|
P/E Ratio | −2.3x | −2.3x | −0.5x | |
PEG Ratio | −0.12 | −0.03 | 0.00 | |
Price/Book | 4.2x | 1.2x | 2.6x | |
Price / LTM Sales | - | 71.4x | 3.2x | |
Upside (Analyst Target) | −68.3% | 242.9% | 44.3% | |
Fair Value Upside | Unlock | 14.0% | 6.6% | Unlock |