Taysha Gene Therapies, Inc., a gene therapy company, focuses on developing and commercializing adeno-associated virus-based gene therapies for the treatment of monogenic diseases of the central nervous system. It primarily develops TSHA-120 for the treatment of giant axonal neuropathy; TSHA-102 for the treatment of Rett syndrome; TSHA-121 for the treatment of CLN7 disease; TSHA-118 for the treatment of CLN1 disease; TSHA-105 for the treatment of for SLC13A5 deficiency; TSHA-113 for the treatment of tauopathies; TSHA-106 for the treatment of angelman syndrome; TSHA-114 for the treatment of fragile X syndrome; and TSHA-101 for the treatment of GM2 gangliosidosis. Taysha Gene Therapies, Inc. has a strategic partnership with The University of Texas Southwestern Medical Center. Taysha Gene Therapies, Inc. was incorporated in 2019 and is headquartered in Dallas, Texas.
Rett Syndrome Frontie | Taysha's TSHA-102 shows promise in treating Rett syndrome, targeting a $2.5 billion market with potential peak revenue of $1 billion by 2035 |
Clinical Progress | Phase 1/2 data reveals consistent improvements across Rett symptoms. Higher dose cohorts initiated early, with crucial data expected in H1 2025 |
Financial Outlook | $76.8M raised extends cash runway to Q4 2026. Analyst targets range from $5 to $7, reflecting cautious optimism amidst ongoing clinical development |
Regulatory Roadmap | RMAT designation may expedite approval. Key meetings with FDA in 2025 could accelerate TSHA-102's path to market, potentially outpacing competitors |
Metrics to compare | TSHA | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipTSHAPeersSector | |
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P/E Ratio | −23.0x | −2.0x | −0.7x | |
PEG Ratio | −0.24 | −0.01 | 0.00 | |
Price/Book | 5.9x | 0.9x | 2.6x | |
Price / LTM Sales | 52.9x | 13.3x | 3.2x | |
Upside (Analyst Target) | 173.4% | 353.5% | 47.1% | |
Fair Value Upside | Unlock | 23.3% | 7.3% | Unlock |