Gene Editing Pionee | Intellia Therapeutics leads in CRISPR/Cas9 technology, with promising clinical trials for hereditary angioedema and transthyretin amyloidosis treatments |
Financial Outlook | Strong $953M cash position supports operations into late 2026, despite current losses. Analyst price targets range from $54 to $76 per share |
Market Potential | Explore Intellia's position in multi-billion dollar markets for HAE and ATTR, with potential to revolutionize treatment through one-time gene editing therapies |
Challenges Ahead | Delve into regulatory hurdles, competition, and public perception issues facing Intellia as it navigates the complex landscape of gene editing technologies |
Intellia Therapeutics, Inc., a genome editing company, focuses on the development of curative therapeutics. The company’s in vivo programs include NTLA-2001, which is in Phase 1 clinical trial for the treatment of transthyretin amyloidosis; NTLA-2002 for the treatment of hereditary angioedema; and NTLA-3001 for alpha-1 antitrypsin deficiency associated lung disease. It also focusses on programs comprising hemophilia A and hemophilia B; and research of proprietary programs focused on developing engineered cell therapies to treat various cancers and autoimmune diseases. In addition, the company offers tools comprising of Clustered, Regularly Interspaced Short Palindromic Repeats/CRISPR associated 9 (CRISPR/Cas9) system. It has license and collaboration agreement with Regeneron Pharmaceuticals, Inc. to co-develop potential products for the treatment of hemophilia A and hemophilia B; AvenCell Therapeutics, Inc. to develop allogeneic universal CAR-T cell therapies, and co-develop and co-commercialize allogeneic universal CAR-T cell products for an immuno-oncology indication; SparingVision SAS to develop novel genomic medicines utilizing CRISPR/Cas9 technology for the treatment of ocular diseases; Kyverna Therapeutics, Inc. for the development of an allogeneic CD19 CAR-T cell therapy for the treatment of a variety of B cell-mediated autoimmune diseases; and ONK Therapeutics, Ltd. for the development of engineered NK cell therapies to cure patients with cancer. Intellia Therapeutics, Inc. was incorporated in 2014 and is headquartered in Cambridge, Massachusetts.
Metrics to compare | NTLA | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipNTLAPeersSector | |
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P/E Ratio | −3.7x | −3.0x | −0.6x | |
PEG Ratio | 5.82 | −0.10 | 0.00 | |
Price/Book | 1.9x | 3.1x | 2.6x | |
Price / LTM Sales | 41.1x | 29.6x | 3.2x | |
Upside (Analyst Target) | 249.8% | 214.0% | 46.9% | |
Fair Value Upside | Unlock | 17.7% | 7.9% | Unlock |